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[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8

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[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8

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Product Description

Prilocaine HCl
1. Purity: 99.8%
2. CAS No.: 1786-81-8
3. White Crystal Powder
4. Local anesthetic.
5. USP/BP standard
[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8
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Product name Prilocaine/Propitocaine Hydrochloride MFG. Date 2018-04-30
Package 1kg/bag Batch number FH2018-04-30
Testing Date 2018-04-30 Exp Date 2020-04-30
Standard USP36 Quantity 800kg
Cas No. 1786-81-8 EINECS 217-244-0
Molecular Formula Cl3H20N2O·HCl Molecular Weight 256.7716
Function Main functions are as follows:
1. Local anesthetic.
Applications Main applications are as follows:
The material for Local anesthetic.
[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8
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Items Tested Specification Result
Characters White or almost white crystalline powder Confirms
Melting Point 166ºC-169ºC 166.5ºC-168.5ºC
Solubility Freely soluble in water and in alcohol Confirms
Assay (HPLC) 99.0--101.0% (calculated on the dried basis) 99.6%
Loss on Drying Not more than 0.3% 0.16%
Related substances Not more than 1.0% 0.11%
Acetone Not more than 5000ppm conforms
Ethanol Not more than 5000ppm conforms
Sulphated ash Not more than 0.15% conforms
Heavy Metal Not more than 0.001% <0.001%
Conclusion Conforms USP36
[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8
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What is Prilocaine?

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a
preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

Applications:

Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical
procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.

[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8
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More details:

Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.

In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.

Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.

Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.
[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8
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Usage and Dosage:

Infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.

Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.

Epidural anesthesia: use 10 to 30 mL of 1.5%~1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600mg.
[email protected] Prilocaine Hcl Propitocaine HCl CAS No.: 1786-81-8
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Email:[email protected]
Whatsapp:+8615072758944

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